This paper-specific evaluation tests protein-ligand binding affinity prediction using CASF-2016.
Explanatory profile: limited source coverage · Automated source review, 2026-09-16. This does not change the review status of its results.
| Property | Description and evidence |
|---|---|
| Record type | Paper-specific task; protocol incompletely extractedImproved Prediction of Ligand–Protein Binding Affinities by Meta-modeling · Table 4, Meta-models row, CASF-2016 Benchmark > PCC column |
| Inputs | CASF-2016Improved Prediction of Ligand–Protein Binding Affinities by Meta-modeling · Table 4, Meta-models row, CASF-2016 Benchmark > PCC column |
| Assessment | Pearson correlationImproved Prediction of Ligand–Protein Binding Affinities by Meta-modeling · Table 4, Meta-models row, CASF-2016 Benchmark > PCC column |
| Recorded split or evaluation setting | core benchmarkImproved Prediction of Ligand–Protein Binding Affinities by Meta-modeling · Table 4, Meta-models row, CASF-2016 Benchmark > PCC column |
| Datasets | Not extracted or verified for this record. |
| Organisms | Not extracted or verified for this record. |
| Assays | Not extracted or verified for this record. |
| Adaptation | Not extracted or verified for this record. |
| Baselines | Not extracted or verified for this record. |
Outline of the existing paper extraction. Split membership, fitting details and scorer implementation remain incompletely reviewed.
The existing paper extraction describes: Sequence-or-structure meta-model; predicts ln(Kd/Ki) using docked and deep-learning components. This description is retained with the exact evaluation records; it is not a new protocol reconstruction.
Improved Prediction of Ligand–Protein Binding Affinities by Meta-modeling · Table 4, Meta-models row, CASF-2016 Benchmark > PCC columnRelease 2026-09-16-d74d282221a9 · 1 evaluation · 1 metric row. Different protocols are not a single leaderboard.
| Metric and finding | Coverage and uncertainty | Evidence |
|---|---|---|
| binding-affinity meta-model: protein-ligand binding affinity prediction Model: binding-affinity meta-model · Benchmark: protein-ligand binding affinity prediction · Dataset: CASF-2016 Sequence-or-structure meta-model; predicts ln(Kd/Ki) using docked and deep-learning components Author-reported evaluation · Evaluation metadata: needs review | ||
| 0.777 Pearson correlation Unit: unitless · Direction: unknown | Uncertainty: not reported in legacy extract Scored: Not reported · Eligible: Not reported | source checkedImproved Prediction of Ligand–Protein Binding Affinities by Meta-modeling · Table 4, Meta-models row, CASF-2016 Benchmark > PCC column Source checking is not independent reproduction. |
Catalogue extraction inspected; protocol claims remain limited to the cited evidence. Missing details are not presumed absent from the original paper.
Stable record: reported-task-77a32496ce8fe6Release 2026-09-16-d74d282221a9 · Record review: needs review
Stable ID: reported-task-77a32496ce8fe6