Strengths and considerations
No source-reviewed explanatory claims are recorded here yet.
model · method
binding-affinity meta-model
binding-affinity meta-model is the method recorded for protein-ligand binding affinity prediction. This page preserves the configuration reported by Improved Prediction of Ligand–Protein Binding Affinities by Meta-modeling.
At a glance
Explanatory profile: limited source coverage · Automated source review, 2026-09-16. This does not change the review status of its results.
| Property | Description and evidence |
|---|---|
| Recorded dataset | CASF-2016Improved Prediction of Ligand–Protein Binding Affinities by Meta-modeling · Table 4, Meta-models row, CASF-2016 Benchmark > PCC column |
| Recorded split | core benchmarkImproved Prediction of Ligand–Protein Binding Affinities by Meta-modeling · Table 4, Meta-models row, CASF-2016 Benchmark > PCC column |
| Model type | Not extracted or verified for this record. |
| Known versions | Not extracted or verified for this record. |
| Training data | Not extracted or verified for this record. |
| Context limits | Not extracted or verified for this record. |
| Access | Not extracted or verified for this record. |
| Code licence | Not extracted or verified for this record. |
| Weights licence | Not extracted or verified for this record. |
How it works
Recorded evaluation
The imported evaluation describes this procedure: Sequence-or-structure meta-model; predicts ln(Kd/Ki) using docked and deep-learning components
Improved Prediction of Ligand–Protein Binding Affinities by Meta-modeling · Table 4, Meta-models row, CASF-2016 Benchmark > PCC columnBenchmarks and results
Release 2026-09-16-d74d282221a9 · 1 evaluation · 1 metric row. Different protocols are not a single leaderboard.
| Metric and finding | Coverage and uncertainty | Evidence |
|---|---|---|
| binding-affinity meta-model: protein-ligand binding affinity prediction Model: binding-affinity meta-model · Benchmark: protein-ligand binding affinity prediction · Dataset: CASF-2016 Sequence-or-structure meta-model; predicts ln(Kd/Ki) using docked and deep-learning components Author-reported evaluation · Evaluation metadata: needs review | ||
| 0.777 Pearson correlation Unit: unitless · Direction: unknown | Uncertainty: not reported in legacy extract Scored: Not reported · Eligible: Not reported | source checkedImproved Prediction of Ligand–Protein Binding Affinities by Meta-modeling · Table 4, Meta-models row, CASF-2016 Benchmark > PCC column Source checking is not independent reproduction. |
Strengths and limitations
Limitations and conditions
- This is an evidence-limited profile. The recorded evaluation context does not establish performance on other datasets or configurations.Improved Prediction of Ligand–Protein Binding Affinities by Meta-modeling · Table 4, Meta-models row, CASF-2016 Benchmark > PCC column
Profile review details
Reviewed the existing release record, its source pointer and linked evaluation context. This is not a fresh full-text architecture review or independent reproduction; numerical review status is unchanged.
Stable record: reported-model-df0efcc0346224Sources and history
Release 2026-09-16-d74d282221a9 · Record review: needs review
- Improved Prediction of Ligand–Protein Binding Affinities by Meta-modeling · Original source · PMC archival version PMC11632770.1
Technical metadata and extraction receipts
Stable ID: reported-model-df0efcc0346224
- areas
- molecular-interactions
- entity level
- method
- version
- Not reported
- reported name
- binding-affinity meta-model
- missing metadata
- version: not_reported_in_legacy_extract; checkpoint revision: not_reported_in_legacy_extract; training data: not_reported_in_legacy_extract; licence: not_reported_in_legacy_extract