0.777 Pearson correlation
binding-affinity meta-model · Pearson correlation · CASF-2016
- Tested model
- binding-affinity meta-model
- Task or benchmark
- protein-ligand binding affinity prediction
- Dataset
- CASF-2016
- Procedure
- Sequence-or-structure meta-model; predicts ln(Kd/Ki) using docked and deep-learning components
- Evaluation
- binding-affinity meta-model: protein-ligand binding affinity prediction
- Evidence
- Author-reported evaluation · source checkedImproved Prediction of Ligand–Protein Binding Affinities by Meta-modeling · Table 4, Meta-models row, CASF-2016 Benchmark > PCC column
A source-checked result verifies the numerical transcription, not every model or protocol detail. Evaluation metadata: needs review. Source checked does not mean independently reproduced.
Evaluation results
Release 2026-09-16-d74d282221a9 · 1 evaluation · 1 metric row. Different protocols are not a single leaderboard.
| Metric and finding | Coverage and uncertainty | Evidence |
|---|---|---|
| binding-affinity meta-model: protein-ligand binding affinity prediction Model: binding-affinity meta-model · Benchmark: protein-ligand binding affinity prediction · Dataset: CASF-2016 Sequence-or-structure meta-model; predicts ln(Kd/Ki) using docked and deep-learning components Author-reported evaluation · Evaluation metadata: needs review | ||
| 0.777 Pearson correlation Unit: unitless · Direction: unknown | Uncertainty: not reported in legacy extract Scored: Not reported · Eligible: Not reported | source checkedImproved Prediction of Ligand–Protein Binding Affinities by Meta-modeling · Table 4, Meta-models row, CASF-2016 Benchmark > PCC column Source checking is not independent reproduction. |
Sources and history
Release 2026-09-16-d74d282221a9 · Record review: source checked
- Improved Prediction of Ligand–Protein Binding Affinities by Meta-modeling · Original source · PMC archival version PMC11632770.1
Technical metadata and extraction receipts
Stable ID: lit-b4-021
- areas
- molecular-interactions
- tasks
- protein-ligand binding affinity prediction
- printed value
- 0.777
- numeric value
- 0.777
- metric
- Pearson correlation
- metric direction
- unknown
- unit
- unitless
- uncertainty
- Not reported
- source locator
- Table 4, Meta-models row, CASF-2016 Benchmark > PCC column
- review
- method: independent_ai_table_review; reviewer: Codex primary curator table review; reviewed at: 2026-09-16T10:41:06Z; notes: Meta-models CASF-2016 PCC. Confirmed XML training-set rowspan inherits preceding row, so0.777 maps to PCC. Transcription verified; experimental claims not independently reproduced.; evidence: 0.777; artifact sha256: 0be25fe75bc0b2eb8065136555763bbae5964ea3a8fdb8c5de79ff96445f6a29; retrieval url: https://www.ebi.ac.uk/europepmc/webservices/rest/PMC11632770/fullTextXML
- legacy id
- lit-b4-021
- legacy row
- id: lit-b4-021; paper id: ligand-affinity-meta-model-2024; domain id: molecular-interactions; task: protein-ligand binding affinity prediction; model: binding-affinity meta-model; model version: Not reported; dataset: CASF-2016; dataset version: Not reported; split: core benchmark; metric: Pearson correlation; value: 0.777; unit: unitless; uncertainty: Not reported; protocol: Sequence-or-structure meta-model; predicts ln(Kd/Ki) using docked and deep-learning components; source locator: Table 4, Meta-models row, CASF-2016 Benchmark > PCC column; source url: https://pmc.ncbi.nlm.nih.gov/articles/PMC11632770/; evaluation origin: author_reported; reviewed utc: 2026-09-15T23:37:05Z
- missing metadata
- model version: not_reported_in_legacy_extract; dataset version: not_reported_in_legacy_extract; uncertainty: not_reported_in_legacy_extract