This paper-specific evaluation tests Lipid–protein binding pose using LiPP lipid–protein complexes.
Explanatory profile: limited source coverage · Automated source review, 2026-09-16. This does not change the review status of its results.
| Property | Description and evidence |
|---|---|
| Record type | Paper-specific task; protocol incompletely extractedThe LiPP Benchmark Set for Modeling Lipid–Protein Complexes: Comparison of Co-Folding and Docking Methods · Table 2, Chai-1 row, LiPP (N=331) % Success Rate column; Table 2, DiffDock-L row, LiPP (N=331) % Success Rate column |
| Inputs | LiPP lipid–protein complexesThe LiPP Benchmark Set for Modeling Lipid–Protein Complexes: Comparison of Co-Folding and Docking Methods · Table 2, Chai-1 row, LiPP (N=331) % Success Rate column; Table 2, DiffDock-L row, LiPP (N=331) % Success Rate column |
| Assessment | Success rate, ligand all-atom RMSD <2 ÅThe LiPP Benchmark Set for Modeling Lipid–Protein Complexes: Comparison of Co-Folding and Docking Methods · Table 2, Chai-1 row, LiPP (N=331) % Success Rate column; Table 2, DiffDock-L row, LiPP (N=331) % Success Rate column |
| Recorded split or evaluation setting | UnextractedThe LiPP Benchmark Set for Modeling Lipid–Protein Complexes: Comparison of Co-Folding and Docking Methods · Table 2, Chai-1 row, LiPP (N=331) % Success Rate column; Table 2, DiffDock-L row, LiPP (N=331) % Success Rate column |
| Datasets | Not extracted or verified for this record. |
| Organisms | Not extracted or verified for this record. |
| Assays | Not extracted or verified for this record. |
| Adaptation | Not extracted or verified for this record. |
| Baselines | Not extracted or verified for this record. |
Outline of the existing paper extraction. Split membership, fitting details and scorer implementation remain incompletely reviewed.
The existing paper extraction describes: Top-scoring pose; all-atom lipid RMSD below 2 Å. This description is retained with the exact evaluation records; it is not a new protocol reconstruction.
The LiPP Benchmark Set for Modeling Lipid–Protein Complexes: Comparison of Co-Folding and Docking Methods · Table 2, Chai-1 row, LiPP (N=331) % Success Rate column; Table 2, DiffDock-L row, LiPP (N=331) % Success Rate columnRelease 2026-09-16-d74d282221a9 · 2 evaluations · 2 metric rows. Different protocols are not a single leaderboard.
| Metric and finding | Coverage and uncertainty | Evidence |
|---|---|---|
| Chai-1: Lipid–protein binding pose Top-scoring pose; all-atom lipid RMSD below 2 Å. Independent external evaluation · Evaluation metadata: needs review | ||
| 60.7 Success rate, ligand all-atom RMSD <2 Å Unit: % · Direction: unknown | Uncertainty: 95% CI 55.2–66.0 Scored: Not reported · Eligible: Not reported | source checkedThe LiPP Benchmark Set for Modeling Lipid–Protein Complexes: Comparison of Co-Folding and Docking Methods · Table 2, Chai-1 row, LiPP (N=331) % Success Rate column Source checking is not independent reproduction. |
| DiffDock-L: Lipid–protein binding pose Top-scoring pose; all-atom lipid RMSD below 2 Å. Independent external evaluation · Evaluation metadata: needs review | ||
| 46.8 Success rate, ligand all-atom RMSD <2 Å Unit: % · Direction: unknown | Uncertainty: 95% CI 41.3–52.3 Scored: Not reported · Eligible: Not reported | source checkedThe LiPP Benchmark Set for Modeling Lipid–Protein Complexes: Comparison of Co-Folding and Docking Methods · Table 2, DiffDock-L row, LiPP (N=331) % Success Rate column Source checking is not independent reproduction. |
Catalogue extraction inspected; protocol claims remain limited to the cited evidence. Missing details are not presumed absent from the original paper.
Stable record: reported-task-ff2dec63c5a3ddRelease 2026-09-16-d74d282221a9 · Record review: needs review
Stable ID: reported-task-ff2dec63c5a3dd