PGLM
Protein foundation model evaluated by the PFMBench authors under their fine-tuning protocol. Input family: Sequence.
Overview
Protein foundation model evaluated by the PFMBench authors under their fine-tuning protocol. Input family: Sequence.
Consult the linked sources for architecture or protocol details. Missing evidence is not evidence of a missing capability.
Evaluations and results
Release 2026-09-17-134cd1815de8 · 12 evaluations · 12 metric rows. Different protocols are not a single leaderboard. Where several source tables report the same metric, the published comparisons above offer a pooled view that names what it does not hold constant.
| Metric and finding | Coverage and uncertainty | Evidence |
|---|---|---|
| PGLM on PFMBench ANTI-RES: Antibiotic resistance Configuration: PGLMTask: PFMBench ANTI-RES: Antibiotic resistanceDataset subset: Antibiotic resistance (PFMBench split) Fine-tuned with an adapter under the PFMBench harness; train, validation and test counts are in Table 1. Author-reported evaluation · Evaluation metadata: source checked | ||
| 0.67257 accuracy Unit: fraction · Direction: higher | Uncertainty: Not reported Scored: Not reported · Eligible: Not reported | source checkedpfmbench primary benchmark evidence · Table 3, row(PGLM [ 5 ]), column(Anti.Res.) Source checking is not independent reproduction. |
| PGLM on PFMBench BINDING-DB: BindingDB Fine-tuned with an adapter under the PFMBench harness; train, validation and test counts are in Table 1. Author-reported evaluation · Evaluation metadata: source checked | ||
| 0.16884 spearman Unit: correlation · Direction: higher | Uncertainty: Not reported Scored: Not reported · Eligible: Not reported | source checkedpfmbench primary benchmark evidence · Table 3, row(PGLM [ 5 ]), column(Bind. DB) Source checking is not independent reproduction. |
| PGLM on PFMBench CLONING-CLF: Cloning CLF Configuration: PGLMTask: PFMBench CLONING-CLF: Cloning CLFDataset subset: Cloning CLF (PFMBench split) Fine-tuned with an adapter under the PFMBench harness; train, validation and test counts are in Table 1. Author-reported evaluation · Evaluation metadata: source checked | ||
| 0.83638 auroc Unit: fraction · Direction: higher | Uncertainty: Not reported Scored: Not reported · Eligible: Not reported | source checkedpfmbench primary benchmark evidence · Table 3, row(PGLM [ 5 ]), column(Clo. CLF) Source checking is not independent reproduction. |
| PGLM on PFMBench DEEPLOC2: DeepLoc2 Multi Configuration: PGLMTask: PFMBench DEEPLOC2: DeepLoc2 MultiDataset subset: DeepLoc2 Multi (PFMBench split) Fine-tuned with an adapter under the PFMBench harness; train, validation and test counts are in Table 1. Author-reported evaluation · Evaluation metadata: source checked | ||
| 0.74772 f1 Unit: fraction · Direction: higher | Uncertainty: Not reported Scored: Not reported · Eligible: Not reported | source checkedpfmbench primary benchmark evidence · Table 3, row(PGLM [ 5 ]), column(DL2 M.) Source checking is not independent reproduction. |
| PGLM on PFMBench DEEPSOL: DeepSol Fine-tuned with an adapter under the PFMBench harness; train, validation and test counts are in Table 1. Author-reported evaluation · Evaluation metadata: source checked | ||
| 0.82160 auroc Unit: fraction · Direction: higher | Uncertainty: Not reported Scored: Not reported · Eligible: Not reported | source checkedpfmbench primary benchmark evidence · Table 3, row(PGLM [ 5 ]), column(DeepSol) Source checking is not independent reproduction. |
| PGLM on PFMBench EC: Enzyme Commission Configuration: PGLMTask: PFMBench EC: Enzyme CommissionDataset subset: Enzyme Commission (PFMBench split) Fine-tuned with an adapter under the PFMBench harness; train, validation and test counts are in Table 1. Author-reported evaluation · Evaluation metadata: source checked | ||
| 0.74659 f1 Unit: fraction · Direction: higher | Uncertainty: Not reported Scored: Not reported · Eligible: Not reported | source checkedpfmbench primary benchmark evidence · Table 3, row(PGLM [ 5 ]), column(EC) Source checking is not independent reproduction. |
| PGLM on PFMBench MAT-PROD: Material production Configuration: PGLMTask: PFMBench MAT-PROD: Material productionDataset subset: Material production (PFMBench split) Fine-tuned with an adapter under the PFMBench harness; train, validation and test counts are in Table 1. Author-reported evaluation · Evaluation metadata: source checked | ||
| 0.79495 accuracy Unit: fraction · Direction: higher | Uncertainty: Not reported Scored: Not reported · Eligible: Not reported | source checkedpfmbench primary benchmark evidence · Table 3, row(PGLM [ 5 ]), column(Mat.Pro.) Source checking is not independent reproduction. |
| PGLM on PFMBench METAL-ION: Metal ion binding Configuration: PGLMTask: PFMBench METAL-ION: Metal ion bindingDataset subset: Metal ion binding (PFMBench split) Fine-tuned with an adapter under the PFMBench harness; train, validation and test counts are in Table 1. Author-reported evaluation · Evaluation metadata: source checked | ||
| 0 .74513 accuracy Unit: fraction · Direction: higher | Uncertainty: Not reported Scored: Not reported · Eligible: Not reported | source checkedpfmbench primary benchmark evidence · Table 3, row(PGLM [ 5 ]), column(M. I. Bin.) Source checking is not independent reproduction. |
| PGLM on PFMBench PDB-BIND: PDBbind Fine-tuned with an adapter under the PFMBench harness; train, validation and test counts are in Table 1. Author-reported evaluation · Evaluation metadata: source checked | ||
| 0.16877 spearman Unit: correlation · Direction: higher | Uncertainty: Not reported Scored: Not reported · Eligible: Not reported | source checkedpfmbench primary benchmark evidence · Table 3, row(PGLM [ 5 ]), column(PDBBind) Source checking is not independent reproduction. |
| PGLM on PFMBench PROTEINGYM-ZS: ProteinGym zero-shot variant effect prediction Configuration: PGLMTask: PFMBench PROTEINGYM-ZS: ProteinGym zero-shot variant effect predictionDataset subset: ProteinGym (PFMBench split) Scored zero-shot, with no fine-tuning, as reported in PFMBench Table 4. Author-reported evaluation · Evaluation metadata: source checked | ||
| 0.39750 spearman Unit: correlation · Direction: higher | Uncertainty: Not reported Scored: Not reported · Eligible: Not reported | source checkedpfmbench primary benchmark evidence · Table 4, row(PGLM [ 5 ]), column(ProteinGym) Source checking is not independent reproduction. |
| PGLM on PFMBench SEC-STRUCT: Secondary structure Configuration: PGLMTask: PFMBench SEC-STRUCT: Secondary structureDataset subset: Secondary structure (PFMBench split) Fine-tuned with an adapter under the PFMBench harness; train, validation and test counts are in Table 1. Author-reported evaluation · Evaluation metadata: source checked | ||
| 0.72842 accuracy Unit: fraction · Direction: higher | Uncertainty: Not reported Scored: Not reported · Eligible: Not reported | source checkedpfmbench primary benchmark evidence · Table 3, row(PGLM [ 5 ]), column(Sec. Str.) Source checking is not independent reproduction. |
| PGLM on PFMBench STABILITY: TAPE_Stability Configuration: PGLMTask: PFMBench STABILITY: TAPE_StabilityDataset subset: TAPE_Stability (PFMBench split) Fine-tuned with an adapter under the PFMBench harness; train, validation and test counts are in Table 1. Author-reported evaluation · Evaluation metadata: source checked | ||
| 0 .33127 spearman Unit: correlation · Direction: higher | Uncertainty: Not reported Scored: Not reported · Eligible: Not reported | source checkedpfmbench primary benchmark evidence · Table 3, row(PGLM [ 5 ]), column(Stability) Source checking is not independent reproduction. |
Evidence table
Inspect claims, sources and review details
Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.
One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.
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| Property and statement | Original source and location | Review and provenance |
|---|
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Sources and history
Release 2026-09-17-134cd1815de8 · Record review: source checked
1 source records and release history
- pfmbench primary benchmark evidence · Original source · 2506.14796v1
Technical metadata and extraction receipts
Stable ID: pfmbench-method-pglm
- areas
- proteins-complexes
- source locator
- Table 3, row(PGLM [ 5 ])
- missing metadata
- checkpoint revision: unreported; parameters: unextracted
Related records
- model: PGLM on PFMBench ANTI-RES: Antibiotic resistance
- model: PGLM on PFMBench BINDING-DB: BindingDB
- model: PGLM on PFMBench CLONING-CLF: Cloning CLF
- model: PGLM on PFMBench DEEPLOC2: DeepLoc2 Multi
- model: PGLM on PFMBench DEEPSOL: DeepSol
- model: PGLM on PFMBench EC: Enzyme Commission
- model: PGLM on PFMBench MAT-PROD: Material production
- model: PGLM on PFMBench METAL-ION: Metal ion binding
- model: PGLM on PFMBench PDB-BIND: PDBbind
- model: PGLM on PFMBench PROTEINGYM-ZS: ProteinGym zero-shot variant effect prediction
- model: PGLM on PFMBench SEC-STRUCT: Secondary structure
- model: PGLM on PFMBench STABILITY: TAPE_Stability