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evaluation · needs review

ESM-2: Mutated RBD binding prediction

Evaluation procedure

Frozen mean-pooled representation with downstream regression; position-stratified split.

Model
ESM-2
Benchmark
Mutated RBD binding prediction
Dataset
PRIME mutated RBD
origin
Independent external evaluation
configuration
8M
protocol id
Not reported
dataset version
Not reported
split
position-stratified
population
Not reported
inputs
Not reported
adaptation
Not reported
metric implementation
Not reported
aggregation
Not reported
budget
Not reported

Metadata review: needs review. Unreported conditions prevent automatic comparisons.

Evaluation results

Release 2026-09-16-d74d282221a9 · 1 evaluation · 1 metric row. Different protocols are not a single leaderboard.

Results grouped by the exact reported evaluation
Metric and findingCoverage and uncertaintyEvidence
ESM-2: Mutated RBD binding prediction

Frozen mean-pooled representation with downstream regression; position-stratified split.

Independent external evaluation · Evaluation metadata: needs review

0.0248

Unit: unitless · Direction: unknown

Uncertainty: ± 0.01

Scored: Not reported · Eligible: Not reported

source checkedPRIME: An evaluation framework for protein representation inference and generalization in viral mutation space · Table 1, ESM-2 8M / Mean / not fine-tuned row, Position-Stratified Split Binding R² column

Source checking is not independent reproduction.

Sources and history

Release 2026-09-16-d74d282221a9 · Record review: needs review

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Technical metadata and extraction receipts

Stable ID: evaluation-lit-021

areas
proteins-complexes
tasks
Mutated RBD binding prediction
origin
independent_paper
protocol
Frozen mean-pooled representation with downstream regression; position-stratified split.
version
8M
comparison
protocol id: Not reported; dataset version: Not reported; split: position-stratified; population: Not reported; inputs: Not reported; adaptation: Not reported; metric implementation: Not reported; aggregation: Not reported; budget: Not reported
missing metadata
dataset version: not_reported_in_legacy_extract
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