evaluation · needs review
ESM-2: Mutated RBD binding prediction
Evaluation procedure
Frozen mean-pooled representation with downstream regression; position-stratified split.
- Model
- ESM-2
- Benchmark
- Mutated RBD binding prediction
- Dataset
- PRIME mutated RBD
- origin
- Independent external evaluation
- configuration
- 8M
- protocol id
- Not reported
- dataset version
- Not reported
- split
- position-stratified
- population
- Not reported
- inputs
- Not reported
- adaptation
- Not reported
- metric implementation
- Not reported
- aggregation
- Not reported
- budget
- Not reported
Metadata review: needs review. Unreported conditions prevent automatic comparisons.
Evaluation results
Release 2026-09-16-d74d282221a9 · 1 evaluation · 1 metric row. Different protocols are not a single leaderboard.
| Metric and finding | Coverage and uncertainty | Evidence |
|---|---|---|
| ESM-2: Mutated RBD binding prediction Frozen mean-pooled representation with downstream regression; position-stratified split. Independent external evaluation · Evaluation metadata: needs review | ||
| 0.0248 R² Unit: unitless · Direction: unknown | Uncertainty: ± 0.01 Scored: Not reported · Eligible: Not reported | source checkedPRIME: An evaluation framework for protein representation inference and generalization in viral mutation space · Table 1, ESM-2 8M / Mean / not fine-tuned row, Position-Stratified Split Binding R² column Source checking is not independent reproduction. |
Sources and history
Release 2026-09-16-d74d282221a9 · Record review: needs review
- PRIME: An evaluation framework for protein representation inference and generalization in viral mutation space · Original source · version of record
Technical metadata and extraction receipts
Stable ID: evaluation-lit-021
- areas
- proteins-complexes
- tasks
- Mutated RBD binding prediction
- origin
- independent_paper
- protocol
- Frozen mean-pooled representation with downstream regression; position-stratified split.
- version
- 8M
- comparison
- protocol id: Not reported; dataset version: Not reported; split: position-stratified; population: Not reported; inputs: Not reported; adaptation: Not reported; metric implementation: Not reported; aggregation: Not reported; budget: Not reported
- missing metadata
- dataset version: not_reported_in_legacy_extract
Related records
- model: ESM-2
- benchmark: Mutated RBD binding prediction
- dataset: PRIME mutated RBD
- evaluation: ESM-2 · R² · PRIME mutated RBD