Strengths and considerations
No source-reviewed explanatory claims are recorded here yet.
model · method
ESM-2
ESM-2 is the method recorded for Mutated RBD binding prediction. This page preserves the configuration reported by PRIME: An evaluation framework for protein representation inference and generalization in viral mutation space.
At a glance
Explanatory profile: limited source coverage · Automated source review, 2026-09-16. This does not change the review status of its results.
| Property | Description and evidence |
|---|---|
| Recorded dataset | PRIME mutated RBDPRIME: An evaluation framework for protein representation inference and generalization in viral mutation space · Table 1, ESM-2 8M / Mean / not fine-tuned row, Position-Stratified Split Binding R² column |
| Recorded split | position-stratifiedPRIME: An evaluation framework for protein representation inference and generalization in viral mutation space · Table 1, ESM-2 8M / Mean / not fine-tuned row, Position-Stratified Split Binding R² column |
| Recorded configuration | 8MPRIME: An evaluation framework for protein representation inference and generalization in viral mutation space · Table 1, ESM-2 8M / Mean / not fine-tuned row, Position-Stratified Split Binding R² column |
| Model type | Not extracted or verified for this record. |
| Training data | Not extracted or verified for this record. |
| Context limits | Not extracted or verified for this record. |
| Access | Not extracted or verified for this record. |
| Code licence | Not extracted or verified for this record. |
| Weights licence | Not extracted or verified for this record. |
How it works
Recorded evaluation
The imported evaluation describes this procedure: Frozen mean-pooled representation with downstream regression; position-stratified split.
PRIME: An evaluation framework for protein representation inference and generalization in viral mutation space · Table 1, ESM-2 8M / Mean / not fine-tuned row, Position-Stratified Split Binding R² columnBenchmarks and results
Release 2026-09-16-d74d282221a9 · 1 evaluation · 1 metric row. Different protocols are not a single leaderboard.
| Metric and finding | Coverage and uncertainty | Evidence |
|---|---|---|
| ESM-2: Mutated RBD binding prediction Frozen mean-pooled representation with downstream regression; position-stratified split. Independent external evaluation · Evaluation metadata: needs review | ||
| 0.0248 R² Unit: unitless · Direction: unknown | Uncertainty: ± 0.01 Scored: Not reported · Eligible: Not reported | source checkedPRIME: An evaluation framework for protein representation inference and generalization in viral mutation space · Table 1, ESM-2 8M / Mean / not fine-tuned row, Position-Stratified Split Binding R² column Source checking is not independent reproduction. |
Strengths and limitations
Limitations and conditions
- This is an evidence-limited profile. The recorded evaluation context does not establish performance on other datasets or configurations.PRIME: An evaluation framework for protein representation inference and generalization in viral mutation space · Table 1, ESM-2 8M / Mean / not fine-tuned row, Position-Stratified Split Binding R² column
Profile review details
Reviewed the existing release record, its source pointer and linked evaluation context. This is not a fresh full-text architecture review or independent reproduction; numerical review status is unchanged.
Stable record: reported-model-d0d5df2beb02b2Sources and history
Release 2026-09-16-d74d282221a9 · Record review: needs review
- PRIME: An evaluation framework for protein representation inference and generalization in viral mutation space · Original source · version of record
Technical metadata and extraction receipts
Stable ID: reported-model-d0d5df2beb02b2
- areas
- proteins-complexes
- entity level
- method
- version
- 8M
- reported name
- ESM-2
- missing metadata
- checkpoint revision: not_reported_in_legacy_extract; training data: not_reported_in_legacy_extract; licence: not_reported_in_legacy_extract