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Task

DART-Eval CTS-H1ESC: Cell-type-specific element classification, H1ESC

Cell-type-specific element classification, H1ESC. Scored with AUROC on ENCODE chromatin accessibility peaks in five cell lines. One-against-rest AUROC for H1ESC accessible elements.

14 evaluations · 14 metric rows

Overview

Cell-type-specific element classification, H1ESC. Scored with AUROC on ENCODE chromatin accessibility peaks in five cell lines. One-against-rest AUROC for H1ESC accessible elements.

Consult the linked sources for architecture or protocol details. Missing evidence is not evidence of a missing capability.

Evaluation design

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Benchmarks

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Recorded evaluations

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Run instructions

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Published comparisons

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DART-Eval CTS-H1ESC: Cell-type-specific element classification, H1ESC

auroc (fraction) · Higher values are better for this metric.

Every method DART-Eval reports on Cell-type-specific element classification, H1ESC, scored with AUROC on ENCODE chromatin accessibility peaks in five cell lines.

Evaluation protocol · ENCODE chromatin accessibility peaks in five cell lines (DART-Eval split)

  1. Caduceus (probed) · Configuration · Author-reported evaluation0.622
  2. DNABERT-2 (probed) · Configuration · Author-reported evaluation0.757
  3. GENA-LM (probed) · Configuration · Author-reported evaluation0.787
  4. HyenaDNA (probed) · Configuration · Author-reported evaluation0.889
  5. Mistral-DNA (probed) · Configuration · Author-reported evaluation0.678
  6. Caduceus (fine-tuned) · Configuration · Author-reported evaluation0.937
  7. DNABERT-2 (fine-tuned) · Configuration · Author-reported evaluation0.930
  8. GENA-LM (fine-tuned) · Configuration · Author-reported evaluation0.923
  9. HyenaDNA (fine-tuned) · Configuration · Author-reported evaluation0.906
  10. Probing-head-like (ab initio) · Method · Author-reported evaluation0.836
  11. ChromBPNet-like (ab initio) · Method · Author-reported evaluation0.929

Source order is preserved. Plotted marks show point estimates; uncertainty, where reported, is retained in the printed values and table. Differences do not establish statistical significance.

DART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 4, column(H1ESC AUROC)
Values, uncertainty and evidence
auroc: original source values
Tested entityPrinted valueUncertaintyEvidence
Caduceus (probed) · Configuration0.622 fractionNot reportedAuthor-reported evaluation · source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 4, row(Probed Caduceus), column(CTS-H1ESC)
DNABERT-2 (probed) · Configuration0.757 fractionNot reportedAuthor-reported evaluation · source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 4, row(Probed DNABERT-2), column(CTS-H1ESC)
GENA-LM (probed) · Configuration0.787 fractionNot reportedAuthor-reported evaluation · source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 4, row(Probed GENA-LM), column(CTS-H1ESC)
HyenaDNA (probed) · Configuration0.889 fractionNot reportedAuthor-reported evaluation · source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 4, row(Probed HyenaDNA), column(CTS-H1ESC)
Mistral-DNA (probed) · Configuration0.678 fractionNot reportedAuthor-reported evaluation · source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 4, row(Probed Mistral-DNA), column(CTS-H1ESC)
Nucleotide Transformer (probed) · Configuration0.795 fractionNot reportedAuthor-reported evaluation · source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 4, row(Probed Nucleotide Transformer), column(CTS-H1ESC)
Caduceus (fine-tuned) · Configuration0.937 fractionNot reportedAuthor-reported evaluation · source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 4, row(Fine-Tuned Caduceus), column(CTS-H1ESC)
DNABERT-2 (fine-tuned) · Configuration0.930 fractionNot reportedAuthor-reported evaluation · source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 4, row(Fine-Tuned DNABERT-2), column(CTS-H1ESC)
GENA-LM (fine-tuned) · Configuration0.923 fractionNot reportedAuthor-reported evaluation · source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 4, row(Fine-Tuned GENA-LM), column(CTS-H1ESC)
HyenaDNA (fine-tuned) · Configuration0.906 fractionNot reportedAuthor-reported evaluation · source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 4, row(Fine-Tuned HyenaDNA), column(CTS-H1ESC)
Mistral-DNA (fine-tuned) · Configuration0.762 fractionNot reportedAuthor-reported evaluation · source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 4, row(Fine-Tuned Mistral-DNA), column(CTS-H1ESC)
Nucleotide Transformer (fine-tuned) · Configuration0.925 fractionNot reportedAuthor-reported evaluation · source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 4, row(Fine-Tuned Nucleotide Transformer), column(CTS-H1ESC)
Probing-head-like (ab initio) · Method0.836 fractionNot reportedAuthor-reported evaluation · source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 4, row(Ab initio Probing-head-like), column(CTS-H1ESC)
ChromBPNet-like (ab initio) · Method0.929 fractionNot reportedAuthor-reported evaluation · source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 4, row(Ab initio ChromBPNet-like), column(CTS-H1ESC)
Scope and limitations
  • Author-reported numbers, source checked but not independently reproduced.
  • The evaluation setting is part of the method name: a zero-shot, probed and fine-tuned run of the same model are different entries.
  • Metrics and datasets differ between tasks, so these figures cannot be averaged into one score.

Source transcription and grouping reviewed by automated source review on 2026-09-18. These experiments were not independently reproduced by rewire.

Tested entities and results

Release 2026-09-17-134cd1815de8 · 14 evaluations · 14 metric rows. Different protocols are not a single leaderboard. Where several source tables report the same metric, the published comparisons above offer a pooled view that names what it does not hold constant.

Results grouped by the exact reported evaluation
Metric and findingCoverage and uncertaintyEvidence
Caduceus (fine-tuned) on DART-Eval CTS-H1ESC: Cell-type-specific element classification, H1ESC

One-against-rest AUROC for H1ESC accessible elements.

Author-reported evaluation · Evaluation metadata: source checked

0.937 auroc

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 4, row(Fine-Tuned Caduceus), column(CTS-H1ESC)

Source checking is not independent reproduction.

Caduceus (probed) on DART-Eval CTS-H1ESC: Cell-type-specific element classification, H1ESC

One-against-rest AUROC for H1ESC accessible elements.

Author-reported evaluation · Evaluation metadata: source checked

0.622 auroc

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 4, row(Probed Caduceus), column(CTS-H1ESC)

Source checking is not independent reproduction.

ChromBPNet-like (ab initio) on DART-Eval CTS-H1ESC: Cell-type-specific element classification, H1ESC

One-against-rest AUROC for H1ESC accessible elements.

Author-reported evaluation · Evaluation metadata: source checked

0.929 auroc

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 4, row(Ab initio ChromBPNet-like), column(CTS-H1ESC)

Source checking is not independent reproduction.

DNABERT-2 (fine-tuned) on DART-Eval CTS-H1ESC: Cell-type-specific element classification, H1ESC

One-against-rest AUROC for H1ESC accessible elements.

Author-reported evaluation · Evaluation metadata: source checked

0.930 auroc

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 4, row(Fine-Tuned DNABERT-2), column(CTS-H1ESC)

Source checking is not independent reproduction.

DNABERT-2 (probed) on DART-Eval CTS-H1ESC: Cell-type-specific element classification, H1ESC

One-against-rest AUROC for H1ESC accessible elements.

Author-reported evaluation · Evaluation metadata: source checked

0.757 auroc

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 4, row(Probed DNABERT-2), column(CTS-H1ESC)

Source checking is not independent reproduction.

GENA-LM (fine-tuned) on DART-Eval CTS-H1ESC: Cell-type-specific element classification, H1ESC

One-against-rest AUROC for H1ESC accessible elements.

Author-reported evaluation · Evaluation metadata: source checked

0.923 auroc

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 4, row(Fine-Tuned GENA-LM), column(CTS-H1ESC)

Source checking is not independent reproduction.

GENA-LM (probed) on DART-Eval CTS-H1ESC: Cell-type-specific element classification, H1ESC

One-against-rest AUROC for H1ESC accessible elements.

Author-reported evaluation · Evaluation metadata: source checked

0.787 auroc

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 4, row(Probed GENA-LM), column(CTS-H1ESC)

Source checking is not independent reproduction.

HyenaDNA (fine-tuned) on DART-Eval CTS-H1ESC: Cell-type-specific element classification, H1ESC

One-against-rest AUROC for H1ESC accessible elements.

Author-reported evaluation · Evaluation metadata: source checked

0.906 auroc

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 4, row(Fine-Tuned HyenaDNA), column(CTS-H1ESC)

Source checking is not independent reproduction.

HyenaDNA (probed) on DART-Eval CTS-H1ESC: Cell-type-specific element classification, H1ESC

One-against-rest AUROC for H1ESC accessible elements.

Author-reported evaluation · Evaluation metadata: source checked

0.889 auroc

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 4, row(Probed HyenaDNA), column(CTS-H1ESC)

Source checking is not independent reproduction.

Mistral-DNA (fine-tuned) on DART-Eval CTS-H1ESC: Cell-type-specific element classification, H1ESC

One-against-rest AUROC for H1ESC accessible elements.

Author-reported evaluation · Evaluation metadata: source checked

0.762 auroc

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 4, row(Fine-Tuned Mistral-DNA), column(CTS-H1ESC)

Source checking is not independent reproduction.

Mistral-DNA (probed) on DART-Eval CTS-H1ESC: Cell-type-specific element classification, H1ESC

One-against-rest AUROC for H1ESC accessible elements.

Author-reported evaluation · Evaluation metadata: source checked

0.678 auroc

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 4, row(Probed Mistral-DNA), column(CTS-H1ESC)

Source checking is not independent reproduction.

Nucleotide Transformer (fine-tuned) on DART-Eval CTS-H1ESC: Cell-type-specific element classification, H1ESC

One-against-rest AUROC for H1ESC accessible elements.

Author-reported evaluation · Evaluation metadata: source checked

0.925 auroc

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 4, row(Fine-Tuned Nucleotide Transformer), column(CTS-H1ESC)

Source checking is not independent reproduction.

Nucleotide Transformer (probed) on DART-Eval CTS-H1ESC: Cell-type-specific element classification, H1ESC

One-against-rest AUROC for H1ESC accessible elements.

Author-reported evaluation · Evaluation metadata: source checked

0.795 auroc

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 4, row(Probed Nucleotide Transformer), column(CTS-H1ESC)

Source checking is not independent reproduction.

Probing-head-like (ab initio) on DART-Eval CTS-H1ESC: Cell-type-specific element classification, H1ESC

One-against-rest AUROC for H1ESC accessible elements.

Author-reported evaluation · Evaluation metadata: source checked

0.836 auroc

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedDART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 4, row(Ab initio Probing-head-like), column(CTS-H1ESC)

Source checking is not independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

1 evidence row matching the loaded filters

Claims, original sources and review scope · Release 2026-09-17-134cd1815de8
Property and statementOriginal source and locationReview and provenance
Relationship: part of

discovery-benchmark-dart-eval

Individual claims
DART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA

Original source ↗

Table 4, column(H1ESC AUROC)

Version: 2412.05430v1
Retrieved: 2026-09-17T07:56:09.182117+00:00

source checked

automated source review · 2026-09-18

Audit details

Primary-source transcription with no human sign-off and no independent reproduction.

Field: links:part_of:discovery-benchmark-dart-eval

Claim: dart-eval-association-cts-h1esc

Source artifact SHA-256: 4194b137ba55c9a2c269d119a9afec6ae1bb0feaf17d91433ae483c41221a56b

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

Sources and history

Release 2026-09-17-134cd1815de8 · Record review: source checked

1 source records and release historyDownload this release
Technical metadata and extraction receipts

Stable ID: dart-eval-task-cts-h1esc

areas
dna-genomes
tasks
Cell-type-specific element classification, H1ESC
metric
AUROC
metric direction
higher
dataset
ENCODE chromatin accessibility peaks in five cell lines
protocol
One-against-rest AUROC for H1ESC accessible elements.
source locator
Table 4, column(H1ESC AUROC)
comparison panels
id: dart-eval-panel-cts-h1esc; title: DART-Eval CTS-H1ESC: Cell-type-specific element classification, H1ESC; protocol id: dart-eval-task-cts-h1esc; dataset id: dart-eval-dataset-encode-chromatin-accessibility-peaks-in-five-cell-lines; metric: auroc; unit: fraction; direction: higher; result ids: dart-eval-result-caduceus-probed-cts-h1esc-auroc; dart-eval-result-dnabert-2-probed-cts-h1esc-auroc; dart-eval-result-gena-lm-probed-cts-h1esc-auroc; dart-eval-result-hyenadna-probed-cts-h1esc-auroc; dart-eval-result-mistral-dna-probed-cts-h1esc-auroc; dart-eval-result-nucleotide-transformer-probed-cts-h1esc-auroc; dart-eval-result-caduceus-fine-tuned-cts-h1esc-auroc; dart-eval-result-dnabert-2-fine-tuned-cts-h1esc-auroc; dart-eval-result-gena-lm-fine-tuned-cts-h1esc-auroc; dart-eval-result-hyenadna-fine-tuned-cts-h1esc-auroc; dart-eval-result-mistral-dna-fine-tuned-cts-h1esc-auroc; dart-eval-result-nucleotide-transformer-fine-tuned-cts-h1esc-auroc; dart-eval-result-probing-head-like-ab-initio-cts-h1esc-auroc; dart-eval-result-chrombpnet-like-ab-initio-cts-h1esc-auroc; source ids: evidence-expansion-p2-evidence-discovery-final-dart-4194b137ba55; source locator: Table 4, column(H1ESC AUROC); context: Every method DART-Eval reports on Cell-type-specific element classification, H1ESC, scored with AUROC on ENCODE chromatin accessibility peaks in five cell lines.; caveats: Author-reported numbers, source checked but not independently reproduced.; The evaluation setting is part of the method name: a zero-shot, probed and fine-tuned run of the same model are different entries.; Metrics and datasets differ between tasks, so these figures cannot be averaged into one score.; review: method: automated_source_review; date: 2026-09-18
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