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Biological models

Understand model architectures, biological inputs, access requirements and the evidence from linked evaluations.

59 model records in release 2026-09-22-f58a0f1d267f. Showing 25–48; page 2 of 3.

Evaluated configurations, methods and pipelines are listed separately. Names alone do not establish equivalent models or checkpoints.

  • GEARS

    Single cell

    GEARS predicts transcriptional responses to single- and multi-gene perturbations from single-cell perturbation screens.

    Record: discovery-model-gears

  • Geneformer

    Cells and tissues

    Geneformer represents single-cell transcriptomes as ranked genes and learns contextual gene and cell representations.

  • Genie 3

    Protein structure

    Genie 3 generates protein designs through all-atom equivariant diffusion.

  • GlycanGT

    Glycomics

    GlycanGT learns glycan representations by treating monosaccharides and linkages as graph tokens.

  • METAGENE-1

    Microbes and communities

    METAGENE-1 is an autoregressive DNA/RNA sequence model trained on wastewater metagenomic data.

  • MIMIC

    RNA and transcriptomes · Proteins and complexes

    MIMIC represents DNA, RNA, protein and associated molecular measurements in a shared multimodal model.

  • mRNA-FM

    RNA and transcriptomes

    mRNA-FM encodes coding RNA with codon-level tokens to produce representations for downstream analysis.

  • MSAlign

    Metabolomics

    MSAlign retrieves candidate molecules from tandem mass spectra by aligning pretrained molecular and spectral representations.

  • Nucleotide Transformer

    Genomics

    Nucleotide Transformer is a family of DNA encoders pretrained on human or multispecies sequence corpora.

  • Nucleotide Transformer v2

    DNA and genomes

    Nucleotide Transformer v2 represents DNA using an encoder pretrained on multiple species.

  • OpenFold

    Protein structure

    OpenFold is a trainable PyTorch implementation of AlphaFold 2 and AlphaFold-Multimer workflows.

  • Pangolin

    DNA and genomes

    Pangolin predicts splice-site strength and changes caused by genetic variants.

    Record: catalog-model-pangolin

  • Pangolin

    Genomics

    Pangolin predicts splice-site strength and changes caused by genetic variants.

    Record: discovery-model-pangolin

  • ProkBERT

    Microbes and communities

    ProkBERT is a family of microbial DNA encoders used for sequence representation, promoter prediction and phage identification.

  • ProteinMPNN

    Proteins and complexes

    ProteinMPNN designs amino-acid sequences for a supplied protein backbone.

    Record: catalog-model-proteinmpnn

  • ProteinMPNN

    Protein structure

    ProteinMPNN designs amino-acid sequences for a supplied protein backbone.

    Record: discovery-model-proteinmpnn

  • RFdiffusion

    Protein structure

    RFdiffusion generates protein structures, optionally conditioned on a motif, target or symmetry constraint.

  • RhoFold+

    RNA and transcriptomes

    RhoFold+ predicts RNA three-dimensional structures from RNA sequence with alignment information.

  • RNA-FM

    RNA and transcriptomes

    RNA-FM learns contextual representations of RNA nucleotides for downstream RNA analyses.

    Record: catalog-model-rna-fm

  • RNA-FM

    RNA

    RNA-FM learns contextual representations of RNA nucleotides for downstream RNA analyses.

    Record: discovery-model-rna-fm

  • scFoundation

    Cells and tissues

    scFoundation produces contextual cell and gene representations from gene-expression measurements.

  • scGPT

    Cells and tissues

    scGPT learns representations of single-cell molecular measurements and supports task-specific adaptation.

    Record: catalog-model-scgpt

  • scGPT

    Single cell

    scGPT learns representations of single-cell molecular measurements and supports task-specific adaptation.

    Record: discovery-model-scgpt

  • scVI

    Cells and tissues

    scVI models single-cell RNA counts with a probabilistic latent-variable model that accounts for observed covariates.

    Record: catalog-model-scvi

This index reflects a dated catalogue, not an exhaustive census. Source checking does not mean independent reproduction; compare results only under compatible protocols, datasets and metrics.