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Task

Open Problems label projection ZEBRAFISH-LABS-F1-MACRO: Label projection on Zebrafish (by laboratory), Macro F1 score

Label projection on Zebrafish (by laboratory), Macro F1 score. Scored with Macro F1 score on Zebrafish (by laboratory). 90k cells from zebrafish embryos throughout the first day of development, with and without a knockout of chordin, an important developmental gene. Split into train/test by laboratory. Dimensions: 26022 cells, 25258 genes. 24 cell types (avg. 1084±1156 cells per cell type).

16 evaluations · 16 metric rows

Overview

Label projection on Zebrafish (by laboratory), Macro F1 score. Scored with Macro F1 score on Zebrafish (by laboratory). 90k cells from zebrafish embryos throughout the first day of development, with and without a knockout of chordin, an important developmental gene. Split into train/test by laboratory. Dimensions: 26022 cells, 25258 genes. 24 cell types (avg. 1084±1156 cells per cell type).

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Evaluation design

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Benchmarks

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Recorded evaluations

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Published comparisons

Explore the results reported under one evaluation protocol. Each figure keeps its source, dataset and metric together; it is not a ranking across studies. The pooled view gathers every source table that reports the same metric and names what it does not hold constant.

Open Problems label projection ZEBRAFISH-LABS-F1-MACRO: Label projection on Zebrafish (by laboratory), Macro F1 score

f1-macro (fraction) · Higher values are better for this metric.

Every method Open Problems label projection reports on Label projection on Zebrafish (by laboratory), Macro F1 score, scored with Macro F1 score on Zebrafish (by laboratory).

Evaluation protocol · Zebrafish (by laboratory) (Open Problems label projection split)

  1. True Labels · Method · Author-reported evaluation1
  2. Majority Vote · Configuration · Author-reported evaluation0
  3. Random Labels · Method · Author-reported evaluation0.015063128971038524

Source order is preserved. Plotted marks show point estimates; uncertainty, where reported, is retained in the printed values and table. Differences do not establish statistical significance.

openproblems-label primary benchmark evidence · results, dataset(zebrafish_labs), metric(f1_macro)
Values, uncertainty and evidence
f1-macro: original source values
Tested entityPrinted valueUncertaintyEvidence
K-neighbors classifier (log CP10k) · Configuration0.16437714442609613 fractionNot reportedAuthor-reported evaluation · source checkedopenproblems-label primary benchmark evidence · results, dataset(zebrafish_labs), method(k_neighbors_classifier), paramset(log CP10k), metric(f1_macro)
Logistic regression (log CP10k) · Configuration0.2327128251184122 fractionNot reportedAuthor-reported evaluation · source checkedopenproblems-label primary benchmark evidence · results, dataset(zebrafish_labs), method(logistic_regression), paramset(log CP10k), metric(f1_macro)
True Labels · Method1 fractionNot reportedAuthor-reported evaluation · source checkedopenproblems-label primary benchmark evidence · results, dataset(zebrafish_labs), method(true_labels), paramset(none), metric(f1_macro)
Majority Vote · Configuration0 fractionNot reportedAuthor-reported evaluation · source checkedopenproblems-label primary benchmark evidence · results, dataset(zebrafish_labs), method(majority_vote), paramset(none), metric(f1_macro)
Random Labels · Method0.015063128971038524 fractionNot reportedAuthor-reported evaluation · source checkedopenproblems-label primary benchmark evidence · results, dataset(zebrafish_labs), method(random_labels), paramset(none), metric(f1_macro)
Multilayer perceptron (log CP10k) · Configuration0.20373028688647557 fractionNot reportedAuthor-reported evaluation · source checkedopenproblems-label primary benchmark evidence · results, dataset(zebrafish_labs), method(multilayer_perceptron), paramset(log CP10k), metric(f1_macro)
XGBoost (log CP10k) · Configuration0.21439857736198084 fractionNot reportedAuthor-reported evaluation · source checkedopenproblems-label primary benchmark evidence · results, dataset(zebrafish_labs), method(xgboost), paramset(log CP10k), metric(f1_macro)
Multilayer perceptron (log scran) · Configuration0.1682215736679451 fractionNot reportedAuthor-reported evaluation · source checkedopenproblems-label primary benchmark evidence · results, dataset(zebrafish_labs), method(multilayer_perceptron), paramset(log scran), metric(f1_macro)
K-neighbors classifier (log scran) · Configuration0.1995615455583369 fractionNot reportedAuthor-reported evaluation · source checkedopenproblems-label primary benchmark evidence · results, dataset(zebrafish_labs), method(k_neighbors_classifier), paramset(log scran), metric(f1_macro)
Logistic regression (log scran) · Configuration0.2245866122961815 fractionNot reportedAuthor-reported evaluation · source checkedopenproblems-label primary benchmark evidence · results, dataset(zebrafish_labs), method(logistic_regression), paramset(log scran), metric(f1_macro)
XGBoost (log scran) · Configuration0.19838515450237226 fractionNot reportedAuthor-reported evaluation · source checkedopenproblems-label primary benchmark evidence · results, dataset(zebrafish_labs), method(xgboost), paramset(log scran), metric(f1_macro)
Seurat reference mapping (SCTransform) · Configuration0.28347167382711347 fractionNot reportedAuthor-reported evaluation · source checkedopenproblems-label primary benchmark evidence · results, dataset(zebrafish_labs), method(seurat_reference_mapping), paramset(SCTransform), metric(f1_macro)
scArches+scANVI (Seurat v3 2000 HVG) · Configuration0.21771900557535676 fractionNot reportedAuthor-reported evaluation · source checkedopenproblems-label primary benchmark evidence · results, dataset(zebrafish_labs), method(scarches_scanvi), paramset(Seurat v3 2000 HVG), metric(f1_macro)
scArches+scANVI (All genes) · Configuration0.23106180199762813 fractionNot reportedAuthor-reported evaluation · source checkedopenproblems-label primary benchmark evidence · results, dataset(zebrafish_labs), method(scarches_scanvi), paramset(All genes), metric(f1_macro)
scANVI (Seurat v3 2000 HVG) · Configuration0.2371223938182558 fractionNot reportedAuthor-reported evaluation · source checkedopenproblems-label primary benchmark evidence · results, dataset(zebrafish_labs), method(scanvi), paramset(Seurat v3 2000 HVG), metric(f1_macro)
scANVI (All genes) · Configuration0.263874405982815 fractionNot reportedAuthor-reported evaluation · source checkedopenproblems-label primary benchmark evidence · results, dataset(zebrafish_labs), method(scanvi), paramset(All genes), metric(f1_macro)
Scope and limitations
  • Results published by the Open Problems project, source checked but not independently reproduced.
  • This covers the label projection task at v1.0.0 only, not the whole Open Problems suite.
  • true_labels and random_labels are controls that bound the scale, not competing methods.
  • Preprocessing is part of the run, so the same method appears once per parameter set.

Source transcription and grouping reviewed by automated source review on 2026-09-18. These experiments were not independently reproduced by rewire.

Tested entities and results

Release 2026-09-17-134cd1815de8 · 16 evaluations · 16 metric rows. Different protocols are not a single leaderboard. Where several source tables report the same metric, the published comparisons above offer a pooled view that names what it does not hold constant.

Results grouped by the exact reported evaluation
Metric and findingCoverage and uncertaintyEvidence
K-neighbors classifier (log CP10k) on Open Problems label projection ZEBRAFISH-LABS-F1-MACRO: Label projection on Zebrafish (by laboratory), Macro F1 score

90k cells from zebrafish embryos throughout the first day of development, with and without a knockout of chordin, an important developmental gene. Split into train/test by laboratory. Dimensions: 26022 cells, 25258 genes. 24 cell types (avg. 1084±1156 cells per cell type).

Author-reported evaluation · Evaluation metadata: source checked

0.16437714442609613 f1-macro

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedopenproblems-label primary benchmark evidence · results, dataset(zebrafish_labs), method(k_neighbors_classifier), paramset(log CP10k), metric(f1_macro)

Source checking is not independent reproduction.

K-neighbors classifier (log scran) on Open Problems label projection ZEBRAFISH-LABS-F1-MACRO: Label projection on Zebrafish (by laboratory), Macro F1 score

90k cells from zebrafish embryos throughout the first day of development, with and without a knockout of chordin, an important developmental gene. Split into train/test by laboratory. Dimensions: 26022 cells, 25258 genes. 24 cell types (avg. 1084±1156 cells per cell type).

Author-reported evaluation · Evaluation metadata: source checked

0.1995615455583369 f1-macro

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedopenproblems-label primary benchmark evidence · results, dataset(zebrafish_labs), method(k_neighbors_classifier), paramset(log scran), metric(f1_macro)

Source checking is not independent reproduction.

Logistic regression (log CP10k) on Open Problems label projection ZEBRAFISH-LABS-F1-MACRO: Label projection on Zebrafish (by laboratory), Macro F1 score

90k cells from zebrafish embryos throughout the first day of development, with and without a knockout of chordin, an important developmental gene. Split into train/test by laboratory. Dimensions: 26022 cells, 25258 genes. 24 cell types (avg. 1084±1156 cells per cell type).

Author-reported evaluation · Evaluation metadata: source checked

0.2327128251184122 f1-macro

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedopenproblems-label primary benchmark evidence · results, dataset(zebrafish_labs), method(logistic_regression), paramset(log CP10k), metric(f1_macro)

Source checking is not independent reproduction.

Logistic regression (log scran) on Open Problems label projection ZEBRAFISH-LABS-F1-MACRO: Label projection on Zebrafish (by laboratory), Macro F1 score

90k cells from zebrafish embryos throughout the first day of development, with and without a knockout of chordin, an important developmental gene. Split into train/test by laboratory. Dimensions: 26022 cells, 25258 genes. 24 cell types (avg. 1084±1156 cells per cell type).

Author-reported evaluation · Evaluation metadata: source checked

0.2245866122961815 f1-macro

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedopenproblems-label primary benchmark evidence · results, dataset(zebrafish_labs), method(logistic_regression), paramset(log scran), metric(f1_macro)

Source checking is not independent reproduction.

Majority Vote on Open Problems label projection ZEBRAFISH-LABS-F1-MACRO: Label projection on Zebrafish (by laboratory), Macro F1 score

90k cells from zebrafish embryos throughout the first day of development, with and without a knockout of chordin, an important developmental gene. Split into train/test by laboratory. Dimensions: 26022 cells, 25258 genes. 24 cell types (avg. 1084±1156 cells per cell type).

Author-reported evaluation · Evaluation metadata: source checked

0 f1-macro

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedopenproblems-label primary benchmark evidence · results, dataset(zebrafish_labs), method(majority_vote), paramset(none), metric(f1_macro)

Source checking is not independent reproduction.

Multilayer perceptron (log CP10k) on Open Problems label projection ZEBRAFISH-LABS-F1-MACRO: Label projection on Zebrafish (by laboratory), Macro F1 score

90k cells from zebrafish embryos throughout the first day of development, with and without a knockout of chordin, an important developmental gene. Split into train/test by laboratory. Dimensions: 26022 cells, 25258 genes. 24 cell types (avg. 1084±1156 cells per cell type).

Author-reported evaluation · Evaluation metadata: source checked

0.20373028688647557 f1-macro

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedopenproblems-label primary benchmark evidence · results, dataset(zebrafish_labs), method(multilayer_perceptron), paramset(log CP10k), metric(f1_macro)

Source checking is not independent reproduction.

Multilayer perceptron (log scran) on Open Problems label projection ZEBRAFISH-LABS-F1-MACRO: Label projection on Zebrafish (by laboratory), Macro F1 score

90k cells from zebrafish embryos throughout the first day of development, with and without a knockout of chordin, an important developmental gene. Split into train/test by laboratory. Dimensions: 26022 cells, 25258 genes. 24 cell types (avg. 1084±1156 cells per cell type).

Author-reported evaluation · Evaluation metadata: source checked

0.1682215736679451 f1-macro

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedopenproblems-label primary benchmark evidence · results, dataset(zebrafish_labs), method(multilayer_perceptron), paramset(log scran), metric(f1_macro)

Source checking is not independent reproduction.

Random Labels on Open Problems label projection ZEBRAFISH-LABS-F1-MACRO: Label projection on Zebrafish (by laboratory), Macro F1 score

90k cells from zebrafish embryos throughout the first day of development, with and without a knockout of chordin, an important developmental gene. Split into train/test by laboratory. Dimensions: 26022 cells, 25258 genes. 24 cell types (avg. 1084±1156 cells per cell type).

Author-reported evaluation · Evaluation metadata: source checked

0.015063128971038524 f1-macro

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedopenproblems-label primary benchmark evidence · results, dataset(zebrafish_labs), method(random_labels), paramset(none), metric(f1_macro)

Source checking is not independent reproduction.

scANVI (All genes) on Open Problems label projection ZEBRAFISH-LABS-F1-MACRO: Label projection on Zebrafish (by laboratory), Macro F1 score

90k cells from zebrafish embryos throughout the first day of development, with and without a knockout of chordin, an important developmental gene. Split into train/test by laboratory. Dimensions: 26022 cells, 25258 genes. 24 cell types (avg. 1084±1156 cells per cell type).

Author-reported evaluation · Evaluation metadata: source checked

0.263874405982815 f1-macro

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedopenproblems-label primary benchmark evidence · results, dataset(zebrafish_labs), method(scanvi), paramset(All genes), metric(f1_macro)

Source checking is not independent reproduction.

scANVI (Seurat v3 2000 HVG) on Open Problems label projection ZEBRAFISH-LABS-F1-MACRO: Label projection on Zebrafish (by laboratory), Macro F1 score

90k cells from zebrafish embryos throughout the first day of development, with and without a knockout of chordin, an important developmental gene. Split into train/test by laboratory. Dimensions: 26022 cells, 25258 genes. 24 cell types (avg. 1084±1156 cells per cell type).

Author-reported evaluation · Evaluation metadata: source checked

0.2371223938182558 f1-macro

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedopenproblems-label primary benchmark evidence · results, dataset(zebrafish_labs), method(scanvi), paramset(Seurat v3 2000 HVG), metric(f1_macro)

Source checking is not independent reproduction.

scArches+scANVI (All genes) on Open Problems label projection ZEBRAFISH-LABS-F1-MACRO: Label projection on Zebrafish (by laboratory), Macro F1 score

90k cells from zebrafish embryos throughout the first day of development, with and without a knockout of chordin, an important developmental gene. Split into train/test by laboratory. Dimensions: 26022 cells, 25258 genes. 24 cell types (avg. 1084±1156 cells per cell type).

Author-reported evaluation · Evaluation metadata: source checked

0.23106180199762813 f1-macro

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedopenproblems-label primary benchmark evidence · results, dataset(zebrafish_labs), method(scarches_scanvi), paramset(All genes), metric(f1_macro)

Source checking is not independent reproduction.

scArches+scANVI (Seurat v3 2000 HVG) on Open Problems label projection ZEBRAFISH-LABS-F1-MACRO: Label projection on Zebrafish (by laboratory), Macro F1 score

90k cells from zebrafish embryos throughout the first day of development, with and without a knockout of chordin, an important developmental gene. Split into train/test by laboratory. Dimensions: 26022 cells, 25258 genes. 24 cell types (avg. 1084±1156 cells per cell type).

Author-reported evaluation · Evaluation metadata: source checked

0.21771900557535676 f1-macro

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedopenproblems-label primary benchmark evidence · results, dataset(zebrafish_labs), method(scarches_scanvi), paramset(Seurat v3 2000 HVG), metric(f1_macro)

Source checking is not independent reproduction.

Seurat reference mapping (SCTransform) on Open Problems label projection ZEBRAFISH-LABS-F1-MACRO: Label projection on Zebrafish (by laboratory), Macro F1 score

90k cells from zebrafish embryos throughout the first day of development, with and without a knockout of chordin, an important developmental gene. Split into train/test by laboratory. Dimensions: 26022 cells, 25258 genes. 24 cell types (avg. 1084±1156 cells per cell type).

Author-reported evaluation · Evaluation metadata: source checked

0.28347167382711347 f1-macro

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedopenproblems-label primary benchmark evidence · results, dataset(zebrafish_labs), method(seurat_reference_mapping), paramset(SCTransform), metric(f1_macro)

Source checking is not independent reproduction.

True Labels on Open Problems label projection ZEBRAFISH-LABS-F1-MACRO: Label projection on Zebrafish (by laboratory), Macro F1 score

90k cells from zebrafish embryos throughout the first day of development, with and without a knockout of chordin, an important developmental gene. Split into train/test by laboratory. Dimensions: 26022 cells, 25258 genes. 24 cell types (avg. 1084±1156 cells per cell type).

Author-reported evaluation · Evaluation metadata: source checked

1 f1-macro

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedopenproblems-label primary benchmark evidence · results, dataset(zebrafish_labs), method(true_labels), paramset(none), metric(f1_macro)

Source checking is not independent reproduction.

XGBoost (log CP10k) on Open Problems label projection ZEBRAFISH-LABS-F1-MACRO: Label projection on Zebrafish (by laboratory), Macro F1 score

90k cells from zebrafish embryos throughout the first day of development, with and without a knockout of chordin, an important developmental gene. Split into train/test by laboratory. Dimensions: 26022 cells, 25258 genes. 24 cell types (avg. 1084±1156 cells per cell type).

Author-reported evaluation · Evaluation metadata: source checked

0.21439857736198084 f1-macro

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedopenproblems-label primary benchmark evidence · results, dataset(zebrafish_labs), method(xgboost), paramset(log CP10k), metric(f1_macro)

Source checking is not independent reproduction.

XGBoost (log scran) on Open Problems label projection ZEBRAFISH-LABS-F1-MACRO: Label projection on Zebrafish (by laboratory), Macro F1 score

90k cells from zebrafish embryos throughout the first day of development, with and without a knockout of chordin, an important developmental gene. Split into train/test by laboratory. Dimensions: 26022 cells, 25258 genes. 24 cell types (avg. 1084±1156 cells per cell type).

Author-reported evaluation · Evaluation metadata: source checked

0.19838515450237226 f1-macro

Unit: fraction · Direction: higher

Uncertainty: Not reported

Scored: Not reported · Eligible: Not reported

source checkedopenproblems-label primary benchmark evidence · results, dataset(zebrafish_labs), method(xgboost), paramset(log scran), metric(f1_macro)

Source checking is not independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

1 evidence row matching the loaded filters

Claims, original sources and review scope · Release 2026-09-17-134cd1815de8
Property and statementOriginal source and locationReview and provenance
Relationship: part of

discovery-benchmark-open-problems

Individual claims
openproblems-label primary benchmark evidence

Original source ↗

results, dataset(zebrafish_labs), metric(f1_macro)

Version: v1.0.0
Retrieved: 2026-09-16T21:16:30.026457+00:00

source checked

automated source review · 2026-09-18

Audit details

Primary-source transcription with no human sign-off and no independent reproduction.

Field: links:part_of:discovery-benchmark-open-problems

Claim: open-problems-association-zebrafish-labs-f1-macro

Source artifact SHA-256: e223ab712ff55997a3abe659f280d4ea2952700e767b87e02c434701da9833c1

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

Sources and history

Release 2026-09-17-134cd1815de8 · Record review: source checked

1 source records and release historyDownload this release
Technical metadata and extraction receipts

Stable ID: open-problems-task-zebrafish-labs-f1-macro

areas
cells-tissues
tasks
Label projection on Zebrafish (by laboratory), Macro F1 score
metric
Macro F1 score
metric direction
higher
dataset
Zebrafish (by laboratory)
protocol
90k cells from zebrafish embryos throughout the first day of development, with and without a knockout of chordin, an important developmental gene. Split into train/test by laboratory. Dimensions: 26022 cells, 25258 genes. 24 cell types (avg. 1084±1156 cells per cell type).
source locator
results, dataset(zebrafish_labs), metric(f1_macro)
comparison panels
id: open-problems-panel-zebrafish-labs-f1-macro; title: Open Problems label projection ZEBRAFISH-LABS-F1-MACRO: Label projection on Zebrafish (by laboratory), Macro F1 score; protocol id: open-problems-task-zebrafish-labs-f1-macro; dataset id: open-problems-dataset-zebrafish-by-laboratory; metric: f1-macro; unit: fraction; direction: higher; result ids: open-problems-result-k-neighbors-classifier-log-cp10k-zebrafish-labs-f1-macro-f1-macro; open-problems-result-logistic-regression-log-cp10k-zebrafish-labs-f1-macro-f1-macro; open-problems-result-true-labels-zebrafish-labs-f1-macro-f1-macro; open-problems-result-majority-vote-zebrafish-labs-f1-macro-f1-macro; open-problems-result-random-labels-zebrafish-labs-f1-macro-f1-macro; open-problems-result-multilayer-perceptron-log-cp10k-zebrafish-labs-f1-macro-f1-macro; open-problems-result-xgboost-log-cp10k-zebrafish-labs-f1-macro-f1-macro; open-problems-result-multilayer-perceptron-log-scran-zebrafish-labs-f1-macro-f1-macro; open-problems-result-k-neighbors-classifier-log-scran-zebrafish-labs-f1-macro-f1-macro; open-problems-result-logistic-regression-log-scran-zebrafish-labs-f1-macro-f1-macro; open-problems-result-xgboost-log-scran-zebrafish-labs-f1-macro-f1-macro; open-problems-result-seurat-reference-mapping-sctransform-zebrafish-labs-f1-macro-f1-macro; open-problems-result-scarches-plus-scanvi-seurat-v3-2000-hvg-zebrafish-labs-f1-macro-f1-macro; open-problems-result-scarches-plus-scanvi-all-genes-zebrafish-labs-f1-macro-f1-macro; open-problems-result-scanvi-seurat-v3-2000-hvg-zebrafish-labs-f1-macro-f1-macro; open-problems-result-scanvi-all-genes-zebrafish-labs-f1-macro-f1-macro; source ids: expansion-p3-open-problems; source locator: results, dataset(zebrafish_labs), metric(f1_macro); context: Every method Open Problems label projection reports on Label projection on Zebrafish (by laboratory), Macro F1 score, scored with Macro F1 score on Zebrafish (by laboratory).; caveats: Results published by the Open Problems project, source checked but not independently reproduced.; This covers the label projection task at v1.0.0 only, not the whole Open Problems suite.; true_labels and random_labels are controls that bound the scale, not competing methods.; Preprocessing is part of the run, so the same method appears once per parameter set.; review: method: automated_source_review; date: 2026-09-18
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