Dataset

Protective-antigen classification feature comparison

Dataset and cohort used in the cited comparison. Dataset population counts do not establish successful prediction coverage.

Dataset and evaluation context

A dataset supplies biological observations. The evaluation protocol defines how those observations are split, used and scored.

Evaluation results

Release 2026-09-17-d277315f7d76 · 3 evaluations · 21 metric rows. Different protocols are not a single leaderboard.

Evaluation setupMetricEvidence origin

Results grouped by the exact reported evaluation
Metric and finding	Coverage and uncertainty	Evidence
ESM Only: Protective-antigen classification feature comparison Configuration: ESM OnlyProtocol: Protective-antigen classification feature comparison (vaccine-antigen candidate prediction)Dataset: Protective-antigen classification feature comparison Original 509 features vs ESM 1,280 features vs combined 1,789 features. 372 protection-positive and 3,720 protection-negative samples. Author-reported evaluation · Evaluation metadata: needs review
0.85 ± 0.036 AUPRC Unit: fraction · Direction: higher	Uncertainty: type: reported plus minus type unresolved; value: 0.036 Scored: Not reported · Eligible: Not reported	source checkedEnhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Table 1., row ESM Only, column AUPRC; XML row3 column7 Source checking is not independent reproduction.
0.98 ± 0.004 Specificity Unit: fraction · Direction: higher	Uncertainty: type: reported plus minus type unresolved; value: 0.004 Scored: Not reported · Eligible: Not reported	source checkedEnhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Table 1., row ESM Only, column Specificity; XML row3 column4 Source checking is not independent reproduction.
0.75 ± 0.063 Sensitivity Unit: fraction · Direction: higher	Uncertainty: type: reported plus minus type unresolved; value: 0.063 Scored: Not reported · Eligible: Not reported	source checkedEnhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Table 1., row ESM Only, column Sensitivity; XML row3 column3 Source checking is not independent reproduction.
0.96 ± 0.005 Val Accuracy Unit: fraction · Direction: higher	Uncertainty: type: reported plus minus type unresolved; value: 0.005 Scored: Not reported · Eligible: Not reported	source checkedEnhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Table 1., row ESM Only, column Val Accuracy; XML row3 column2 Source checking is not independent reproduction.
0.77 ± 0.043 MCC Unit: dimensionless · Direction: higher	Uncertainty: type: reported plus minus type unresolved; value: 0.043 Scored: Not reported · Eligible: Not reported	source checkedEnhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Table 1., row ESM Only, column MCC; XML row3 column6 Source checking is not independent reproduction.
0.94 AUROC Unit: fraction · Direction: higher	Uncertainty: unreported Scored: Not reported · Eligible: Not reported	source checkedEnhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Table 1., row ESM Only, column AUROC; XML row3 column8 Source checking is not independent reproduction.
0.96 ± 0.007 Weighted F1 Unit: fraction · Direction: higher	Uncertainty: type: reported plus minus type unresolved; value: 0.007 Scored: Not reported · Eligible: Not reported	source checkedEnhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Table 1., row ESM Only, column Weighted F1; XML row3 column5 Source checking is not independent reproduction.
Combined: Protective-antigen classification feature comparison Configuration: CombinedProtocol: Protective-antigen classification feature comparison (vaccine-antigen candidate prediction)Dataset: Protective-antigen classification feature comparison Original 509 features vs ESM 1,280 features vs combined 1,789 features. 372 protection-positive and 3,720 protection-negative samples. Author-reported evaluation · Evaluation metadata: needs review
0.85 ± 0.021 MCC Unit: dimensionless · Direction: higher	Uncertainty: type: reported plus minus type unresolved; value: 0.021 Scored: Not reported · Eligible: Not reported	source checkedEnhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Table 1., row Combined, column MCC; XML row4 column6 Source checking is not independent reproduction.
0.99 ± 0.004 Specificity Unit: fraction · Direction: higher	Uncertainty: type: reported plus minus type unresolved; value: 0.004 Scored: Not reported · Eligible: Not reported	source checkedEnhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Table 1., row Combined, column Specificity; XML row4 column4 Source checking is not independent reproduction.
0.97 ± 0.004 Weighted F1 Unit: fraction · Direction: higher	Uncertainty: type: reported plus minus type unresolved; value: 0.004 Scored: Not reported · Eligible: Not reported	source checkedEnhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Table 1., row Combined, column Weighted F1; XML row4 column5 Source checking is not independent reproduction.
0.97 ± 0.004 Val Accuracy Unit: fraction · Direction: higher	Uncertainty: type: reported plus minus type unresolved; value: 0.004 Scored: Not reported · Eligible: Not reported	source checkedEnhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Table 1., row Combined, column Val Accuracy; XML row4 column2 Source checking is not independent reproduction.
0.92 ± 0.013 AUPRC Unit: fraction · Direction: higher	Uncertainty: type: reported plus minus type unresolved; value: 0.013 Scored: Not reported · Eligible: Not reported	source checkedEnhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Table 1., row Combined, column AUPRC; XML row4 column7 Source checking is not independent reproduction.
0.83 ± 0.045 Sensitivity Unit: fraction · Direction: higher	Uncertainty: type: reported plus minus type unresolved; value: 0.045 Scored: Not reported · Eligible: Not reported	source checkedEnhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Table 1., row Combined, column Sensitivity; XML row4 column3 Source checking is not independent reproduction.
0.97 AUROC Unit: fraction · Direction: higher	Uncertainty: unreported Scored: Not reported · Eligible: Not reported	source checkedEnhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Table 1., row Combined, column AUROC; XML row4 column8 Source checking is not independent reproduction.
Original: Protective-antigen classification feature comparison Configuration: OriginalProtocol: Protective-antigen classification feature comparison (vaccine-antigen candidate prediction)Dataset: Protective-antigen classification feature comparison Original 509 features vs ESM 1,280 features vs combined 1,789 features. 372 protection-positive and 3,720 protection-negative samples. Author-reported evaluation · Evaluation metadata: needs review
0.94 AUROC Unit: fraction · Direction: higher	Uncertainty: unreported Scored: Not reported · Eligible: Not reported	source checkedEnhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Table 1., row Original, column AUROC; XML row2 column8 Source checking is not independent reproduction.
0.96 ± 0.008 Weighted F1 Unit: fraction · Direction: higher	Uncertainty: type: reported plus minus type unresolved; value: 0.008 Scored: Not reported · Eligible: Not reported	source checkedEnhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Table 1., row Original, column Weighted F1; XML row2 column5 Source checking is not independent reproduction.
0.78 ± 0.046 MCC Unit: dimensionless · Direction: higher	Uncertainty: type: reported plus minus type unresolved; value: 0.046 Scored: Not reported · Eligible: Not reported	source checkedEnhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Table 1., row Original, column MCC; XML row2 column6 Source checking is not independent reproduction.
0.84 ± 0.049 AUPRC Unit: fraction · Direction: higher	Uncertainty: type: reported plus minus type unresolved; value: 0.049 Scored: Not reported · Eligible: Not reported	source checkedEnhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Table 1., row Original, column AUPRC; XML row2 column7 Source checking is not independent reproduction.
0.74 ± 0.071 Sensitivity Unit: fraction · Direction: higher	Uncertainty: type: reported plus minus type unresolved; value: 0.071 Scored: Not reported · Eligible: Not reported	source checkedEnhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Table 1., row Original, column Sensitivity; XML row2 column3 Source checking is not independent reproduction.
0.96 ± 0.008 Val Accuracy Unit: fraction · Direction: higher	Uncertainty: type: reported plus minus type unresolved; value: 0.008 Scored: Not reported · Eligible: Not reported	source checkedEnhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Table 1., row Original, column Val Accuracy; XML row2 column2 Source checking is not independent reproduction.
0.99 ± 0.004 Specificity Unit: fraction · Direction: higher	Uncertainty: type: reported plus minus type unresolved; value: 0.004 Scored: Not reported · Eligible: Not reported	source checkedEnhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Table 1., row Original, column Specificity; XML row2 column4 Source checking is not independent reproduction.

Evidence table

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

6 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-09-17-d277315f7d76
Property and statement	Original source and location	Review and provenance
attributes.reported_population No value recorded Context-only references	Enhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features Original source ↗ Table 1.: Val Accuracy, Protective-antigen classification feature comparison Version: preprint version in PMC Retrieved: 2026-09-17T07:56:15.123850+00:00	missing or unspecified No individual claim review recorded Audit details Field: `attributes.reported_population` Source artifact SHA-256: `b76fff917addd0e9ff8a2fc843496132ecf832d3ceef248e3edf2dbc78baab5f` Hash scope: Exact retrieved primary paper artifact bytes. Inspected artifact
attributes.source_locator Table 1.: Val Accuracy, Protective-antigen classification feature comparison Context-only references	Enhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features Original source ↗ Table 1.: Val Accuracy, Protective-antigen classification feature comparison Version: preprint version in PMC Retrieved: 2026-09-17T07:56:15.123850+00:00	not individually reviewed No individual claim review recorded Audit details Field: `attributes.source_locator` Source artifact SHA-256: `b76fff917addd0e9ff8a2fc843496132ecf832d3ceef248e3edf2dbc78baab5f` Hash scope: Exact retrieved primary paper artifact bytes. Inspected artifact
attributes.split 372 protection-positive and 3,720 protection-negative samples. Context-only references	Enhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features Original source ↗ Table 1.: Val Accuracy, Protective-antigen classification feature comparison Version: preprint version in PMC Retrieved: 2026-09-17T07:56:15.123850+00:00	not individually reviewed No individual claim review recorded Audit details Field: `attributes.split` Source artifact SHA-256: `b76fff917addd0e9ff8a2fc843496132ecf832d3ceef248e3edf2dbc78baab5f` Hash scope: Exact retrieved primary paper artifact bytes. Inspected artifact
attributes.subset Protective-antigen classification feature comparison Context-only references	Enhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features Original source ↗ Table 1.: Val Accuracy, Protective-antigen classification feature comparison Version: preprint version in PMC Retrieved: 2026-09-17T07:56:15.123850+00:00	not individually reviewed No individual claim review recorded Audit details Field: `attributes.subset` Source artifact SHA-256: `b76fff917addd0e9ff8a2fc843496132ecf832d3ceef248e3edf2dbc78baab5f` Hash scope: Exact retrieved primary paper artifact bytes. Inspected artifact
description Dataset and cohort used in the cited comparison. Dataset population counts do not establish successful prediction coverage. Context-only references	Enhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features Original source ↗ Table 1.: Val Accuracy, Protective-antigen classification feature comparison Version: preprint version in PMC Retrieved: 2026-09-17T07:56:15.123850+00:00	not individually reviewed No individual claim review recorded Audit details Field: `description` Source artifact SHA-256: `b76fff917addd0e9ff8a2fc843496132ecf832d3ceef248e3edf2dbc78baab5f` Hash scope: Exact retrieved primary paper artifact bytes. Inspected artifact
name Protective-antigen classification feature comparison Context-only references	Enhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features Original source ↗ Table 1.: Val Accuracy, Protective-antigen classification feature comparison Version: preprint version in PMC Retrieved: 2026-09-17T07:56:15.123850+00:00	not individually reviewed No individual claim review recorded Audit details Field: `name` Source artifact SHA-256: `b76fff917addd0e9ff8a2fc843496132ecf832d3ceef248e3edf2dbc78baab5f` Hash scope: Exact retrieved primary paper artifact bytes. Inspected artifact

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Sources and history

Release 2026-09-17-d277315f7d76 · Record review: needs review

Enhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Original source · preprint version in PMC

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Technical metadata and extraction receipts

Stable ID: paper-dataset-c1edd1f6f7e93d9f6e

areas: proteins-complexes
tasks: vaccine-antigen candidate prediction
split: 372 protection-positive and 3,720 protection-negative samples.
subset: Protective-antigen classification feature comparison
reported population: Not reported
source locator: Table 1.: Val Accuracy, Protective-antigen classification feature comparison
missing metadata: manifest: unextracted; scored count: unreported
entity classification: review date: 2026-09-17; rationale: This record identifies a biological data collection or source-labelled evaluation cohort. Keep its dataset identity; split, assay, taxonomic level, candidate restrictions and comparison context remain attributes rather than automatically becoming new entity kinds.; source ids: part2-vaxign-esm-2024; source locator: Table 1.: Val Accuracy, Protective-antigen classification feature comparison; ambiguities: None recorded

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