Strengths and considerations
No source-reviewed explanatory claims are recorded here yet.
Protective-antigen classification feature comparison · Table 1.. Original 509 features vs ESM 1,280 features vs combined 1,789 features. 372 protection-positive and 3,720 protection-negative samples.
Explanatory profile: limited source coverage · Automated source review, 2026-09-17. Review applies to the cited claims; unresolved fields are listed below. Numerical results retain their own review status.
| Property | Description and evidence |
|---|---|
| Datasets | Not extracted or verified for this record. |
| Organisms | Not extracted or verified for this record. |
| Assays | Not extracted or verified for this record. |
| Splits | Not extracted or verified for this record. |
| Allowed inputs | Not extracted or verified for this record. |
| Adaptation | Not extracted or verified for this record. |
| Metrics | Not extracted or verified for this record. |
| Baselines | Not extracted or verified for this record. |
Original 509 features vs ESM 1,280 features vs combined 1,789 features. 372 protection-positive and 3,720 protection-negative samples.
Benchmarks bring together tasks and protocols. A task describes the biological question; a protocol defines a particular test.
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Each evaluation records what was tested and under which conditions.
Explore the results reported under one evaluation protocol. Each figure keeps its source, dataset and metric together; it is not a ranking across studies.
Val Accuracy (fraction) · Higher values are better for this metric.
Original 509 features vs ESM 1,280 features vs combined 1,789 features. 372 protection-positive and 3,720 protection-negative samples.
Evaluation protocol · Protective-antigen classification feature comparison
Source order is preserved. Plotted marks show point estimates; uncertainty, where reported, is retained in the printed values and table. Differences do not establish statistical significance.
Enhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Table 1.: Val Accuracy, Protective-antigen classification feature comparison| Tested entity | Printed value | Uncertainty | Evidence |
|---|---|---|---|
| Original · Configuration | 0.96 ± 0.008 fraction | type: reported_plus_minus_type_unresolved; value: 0.008 | Author-reported evaluation · source checkedEnhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Table 1., row Original, column Val Accuracy; XML row2 column2 |
| ESM Only · Configuration | 0.96 ± 0.005 fraction | type: reported_plus_minus_type_unresolved; value: 0.005 | Author-reported evaluation · source checkedEnhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Table 1., row ESM Only, column Val Accuracy; XML row3 column2 |
| Combined · Configuration | 0.97 ± 0.004 fraction | type: reported_plus_minus_type_unresolved; value: 0.004 | Author-reported evaluation · source checkedEnhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Table 1., row Combined, column Val Accuracy; XML row4 column2 |
Source transcription and grouping reviewed by automated source review on 2026-09-17. These experiments were not independently reproduced by rewire.
Release 2026-09-17-d277315f7d76 · 3 evaluations · 21 metric rows. Different protocols are not a single leaderboard.
| Metric and finding | Coverage and uncertainty | Evidence |
|---|---|---|
| ESM Only: Protective-antigen classification feature comparison Configuration: ESM OnlyProtocol: Protective-antigen classification feature comparison (vaccine-antigen candidate prediction)Dataset: Protective-antigen classification feature comparison Original 509 features vs ESM 1,280 features vs combined 1,789 features. 372 protection-positive and 3,720 protection-negative samples. Author-reported evaluation · Evaluation metadata: needs review | ||
| 0.85 ± 0.036 AUPRC Unit: fraction · Direction: higher | Uncertainty: type: reported plus minus type unresolved; value: 0.036 Scored: Not reported · Eligible: Not reported | source checkedEnhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Table 1., row ESM Only, column AUPRC; XML row3 column7 Source checking is not independent reproduction. |
| 0.98 ± 0.004 Specificity Unit: fraction · Direction: higher | Uncertainty: type: reported plus minus type unresolved; value: 0.004 Scored: Not reported · Eligible: Not reported | source checkedEnhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Table 1., row ESM Only, column Specificity; XML row3 column4 Source checking is not independent reproduction. |
| 0.75 ± 0.063 Sensitivity Unit: fraction · Direction: higher | Uncertainty: type: reported plus minus type unresolved; value: 0.063 Scored: Not reported · Eligible: Not reported | source checkedEnhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Table 1., row ESM Only, column Sensitivity; XML row3 column3 Source checking is not independent reproduction. |
| 0.96 ± 0.005 Val Accuracy Unit: fraction · Direction: higher | Uncertainty: type: reported plus minus type unresolved; value: 0.005 Scored: Not reported · Eligible: Not reported | source checkedEnhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Table 1., row ESM Only, column Val Accuracy; XML row3 column2 Source checking is not independent reproduction. |
| 0.77 ± 0.043 MCC Unit: dimensionless · Direction: higher | Uncertainty: type: reported plus minus type unresolved; value: 0.043 Scored: Not reported · Eligible: Not reported | source checkedEnhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Table 1., row ESM Only, column MCC; XML row3 column6 Source checking is not independent reproduction. |
| 0.94 AUROC Unit: fraction · Direction: higher | Uncertainty: unreported Scored: Not reported · Eligible: Not reported | source checkedEnhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Table 1., row ESM Only, column AUROC; XML row3 column8 Source checking is not independent reproduction. |
| 0.96 ± 0.007 Weighted F1 Unit: fraction · Direction: higher | Uncertainty: type: reported plus minus type unresolved; value: 0.007 Scored: Not reported · Eligible: Not reported | source checkedEnhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Table 1., row ESM Only, column Weighted F1; XML row3 column5 Source checking is not independent reproduction. |
| Combined: Protective-antigen classification feature comparison Configuration: CombinedProtocol: Protective-antigen classification feature comparison (vaccine-antigen candidate prediction)Dataset: Protective-antigen classification feature comparison Original 509 features vs ESM 1,280 features vs combined 1,789 features. 372 protection-positive and 3,720 protection-negative samples. Author-reported evaluation · Evaluation metadata: needs review | ||
| 0.85 ± 0.021 MCC Unit: dimensionless · Direction: higher | Uncertainty: type: reported plus minus type unresolved; value: 0.021 Scored: Not reported · Eligible: Not reported | source checkedEnhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Table 1., row Combined, column MCC; XML row4 column6 Source checking is not independent reproduction. |
| 0.99 ± 0.004 Specificity Unit: fraction · Direction: higher | Uncertainty: type: reported plus minus type unresolved; value: 0.004 Scored: Not reported · Eligible: Not reported | source checkedEnhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Table 1., row Combined, column Specificity; XML row4 column4 Source checking is not independent reproduction. |
| 0.97 ± 0.004 Weighted F1 Unit: fraction · Direction: higher | Uncertainty: type: reported plus minus type unresolved; value: 0.004 Scored: Not reported · Eligible: Not reported | source checkedEnhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Table 1., row Combined, column Weighted F1; XML row4 column5 Source checking is not independent reproduction. |
| 0.97 ± 0.004 Val Accuracy Unit: fraction · Direction: higher | Uncertainty: type: reported plus minus type unresolved; value: 0.004 Scored: Not reported · Eligible: Not reported | source checkedEnhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Table 1., row Combined, column Val Accuracy; XML row4 column2 Source checking is not independent reproduction. |
| 0.92 ± 0.013 AUPRC Unit: fraction · Direction: higher | Uncertainty: type: reported plus minus type unresolved; value: 0.013 Scored: Not reported · Eligible: Not reported | source checkedEnhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Table 1., row Combined, column AUPRC; XML row4 column7 Source checking is not independent reproduction. |
| 0.83 ± 0.045 Sensitivity Unit: fraction · Direction: higher | Uncertainty: type: reported plus minus type unresolved; value: 0.045 Scored: Not reported · Eligible: Not reported | source checkedEnhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Table 1., row Combined, column Sensitivity; XML row4 column3 Source checking is not independent reproduction. |
| 0.97 AUROC Unit: fraction · Direction: higher | Uncertainty: unreported Scored: Not reported · Eligible: Not reported | source checkedEnhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Table 1., row Combined, column AUROC; XML row4 column8 Source checking is not independent reproduction. |
| Original: Protective-antigen classification feature comparison Configuration: OriginalProtocol: Protective-antigen classification feature comparison (vaccine-antigen candidate prediction)Dataset: Protective-antigen classification feature comparison Original 509 features vs ESM 1,280 features vs combined 1,789 features. 372 protection-positive and 3,720 protection-negative samples. Author-reported evaluation · Evaluation metadata: needs review | ||
| 0.94 AUROC Unit: fraction · Direction: higher | Uncertainty: unreported Scored: Not reported · Eligible: Not reported | source checkedEnhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Table 1., row Original, column AUROC; XML row2 column8 Source checking is not independent reproduction. |
| 0.96 ± 0.008 Weighted F1 Unit: fraction · Direction: higher | Uncertainty: type: reported plus minus type unresolved; value: 0.008 Scored: Not reported · Eligible: Not reported | source checkedEnhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Table 1., row Original, column Weighted F1; XML row2 column5 Source checking is not independent reproduction. |
| 0.78 ± 0.046 MCC Unit: dimensionless · Direction: higher | Uncertainty: type: reported plus minus type unresolved; value: 0.046 Scored: Not reported · Eligible: Not reported | source checkedEnhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Table 1., row Original, column MCC; XML row2 column6 Source checking is not independent reproduction. |
| 0.84 ± 0.049 AUPRC Unit: fraction · Direction: higher | Uncertainty: type: reported plus minus type unresolved; value: 0.049 Scored: Not reported · Eligible: Not reported | source checkedEnhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Table 1., row Original, column AUPRC; XML row2 column7 Source checking is not independent reproduction. |
| 0.74 ± 0.071 Sensitivity Unit: fraction · Direction: higher | Uncertainty: type: reported plus minus type unresolved; value: 0.071 Scored: Not reported · Eligible: Not reported | source checkedEnhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Table 1., row Original, column Sensitivity; XML row2 column3 Source checking is not independent reproduction. |
| 0.96 ± 0.008 Val Accuracy Unit: fraction · Direction: higher | Uncertainty: type: reported plus minus type unresolved; value: 0.008 Scored: Not reported · Eligible: Not reported | source checkedEnhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Table 1., row Original, column Val Accuracy; XML row2 column2 Source checking is not independent reproduction. |
| 0.99 ± 0.004 Specificity Unit: fraction · Direction: higher | Uncertainty: type: reported plus minus type unresolved; value: 0.004 Scored: Not reported · Eligible: Not reported | source checkedEnhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features · Table 1., row Original, column Specificity; XML row2 column4 Source checking is not independent reproduction. |
Last literature check: 2026-09-17. Primary-source discovery and table/protocol screening; source checked is not independently reproduced. Raw acquisitions not automatically numerical publication approval.
| Paper or primary resource | Version | Reference |
|---|---|---|
| Enhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features | preprint version in PMC | Read source DOI: 10.1101/2024.09.04.611295 |
complete comparison tables extracted pending publication review
No source-reviewed explanatory claims are recorded here yet.
No source-reviewed explanatory claims are recorded here yet.
Primary-source transcription and separate automated review. No human sign-off or experimental reproduction.
Stable record: paper-protocol-a7bf3c8f6b432c3093Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.
One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.
3 evidence rows matching the loaded filters
| Property and statement | Original source and location | Review and provenance |
|---|---|---|
| Evaluation in this paper Original 509 features vs ESM 1,280 features vs combined 1,789 features. 372 protection-positive and 3,720 protection-negative samples. Individual claims | Enhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features Table 1.: Val Accuracy, Protective-antigen classification feature comparison Version: preprint version in PMC | source checked automated source review · 2026-09-17 Audit detailsPrimary-source transcription and separate automated review. No human sign-off or experimental reproduction. Field: Source artifact SHA-256: Hash scope: Exact retrieved primary paper artifact bytes. |
| Introduction Protective-antigen classification feature comparison · Table 1.. Original 509 features vs ESM 1,280 features vs combined 1,789 features. 372 protection-positive and 3,720 protection-negative samples. Individual claims | Enhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features Table 1.: Val Accuracy, Protective-antigen classification feature comparison Version: preprint version in PMC | source checked automated source review · 2026-09-17 Audit detailsPrimary-source transcription and separate automated review. No human sign-off or experimental reproduction. Field: Source artifact SHA-256: Hash scope: Exact retrieved primary paper artifact bytes. |
| Relationship: evaluates task reported-task-47465954d606e6 Individual claims | Enhancing Vaxign-DL for Vaccine Candidate Prediction with added ESM-Generated Features Table 1.: Val Accuracy, Protective-antigen classification feature comparison Version: preprint version in PMC | source checked automated source review · 2026-09-17 Audit detailsField: Claim: paper-claim-6875cf87327d9dc4af Source artifact SHA-256: Hash scope: Exact retrieved primary paper artifact bytes. |
Release 2026-09-17-d277315f7d76 · Record review: needs review
Stable ID: paper-protocol-a7bf3c8f6b432c3093